• 介紹：

  藥理藥效：薯蕷皂素是一種植物類固醇,誘導結腸癌細胞凋亡和誘導骨肉瘤細胞凋亡，細胞周期阻滯和COX活性。

• 熔點： 205-208°C

• 沸點： 527.1 °C at 760 mmHg

• 比旋光度： D25 -129° (c = 1.4 in CHCl3)

• 外觀： 白色至淡黃色片狀或針狀結晶

• 溶解性： 二氯甲烷：5mg/ml（需超聲）
  乙醇：1mg/ml（需超聲）
  DMSO：基本不溶
  HPLC檢測建議用二氯甲烷溶解后再用甲醇稀釋，純甲醇溶解性不好。

• 儲存條件： 2-8℃

• 注意：部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

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• 31. [IF=5.195] Suwen Chen et al."Diosgenin attenuates nonalcoholic hepatic steatosis through the hepatic FXR-SHP-SREBP1C/PPARα/CD36 pathway."EUROPEAN JOURNAL OF PHARMACOLOGY.2023 Aug;952:175808

• 30. [IF=5.168] Pan Wang et al."Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay."CHEMICO-BIOLOGICAL INTERACTIONS.2022 Nov;367:110199

• 29. [IF=6.525] Lixia Chen et al."A Novel Diosgenin-Based Liposome Delivery System Combined with Doxorubicin for Liver Cancer Therapy."Pharmaceutics.2022 Aug;14(8):1685

• 28. [IF=6.417] Chen Zhou et al."22R- but not 22S-hydroxycholesterol is recruited for diosgenin biosynthesis."Plant Journal. 2021 Dec 07

• 27. [IF=5.753] Jianghong Gao et al."Molecular Cloning and Functional Characterization of a Sterol 3-O-Glucosyltransferase Involved in Biosynthesis of Steroidal Saponins in Trigonella foenum-graecum.."Front Plant Sci. 2021 Dec;12:809579-809579

• 26. [IF=3.645] Shuo Gu et al."Develop a stepwise integrated method to screen biomarkers of Baihe-Dihuang Tang on the treatment of depression in rats applying with composition screened, untargeted, and targeted metabolomics analysis."Journal Of Separation Science. 2022 M

• 25. [IF=2.289] Zhou Shun et al."Anthelmintic efficacy of natural saponins against Gyrodactylus kobayashii in goldfish (Carassius auratus) and their 3D-QSAR analysis."Parasitol Res. 2021 Mar;120(3):1143-1150

• 24. [IF=3.998] Chengfei Zhang et al."Transcriptome analysis of the effect of diosgenin on autoimmune thyroiditis in a rat model."Sci Rep-Uk. 2021 Mar;11(1):1-12

• 23. [IF=4.242] Shun Zhou et al."Anthelmintic efficacy of 35 herbal medicines against a monogenean parasite, Gyrodactylus kobayashii, infecting goldfish (Carassius auratus)."Aquaculture. 2020 May;521:734992

• 22. [IF=5.275] Liangqun Li et al."Microbial transformation of diosgenin to diosgenone by Wickerhamomyces anomalus JQ-1 obtained from Naxi traditional Jiu Qu."Bioorg Chem. 2020 Jan;95:103508

• 21. [IF=5.923] Lixiu Hou et al."Genome-Wide Identification of CYP72A Gene Family and Expression Patterns Related to Jasmonic Acid Treatment and Steroidal Saponin Accumulation in Dioscorea zingiberensis."Int J Mol Sci. 2021 Jan;22(20):10953

• 20. [IF=0.533] P Wang et al."Ionic Liquid-Based Ultrasonic/Microwave-Assisted Extraction of Steroidal Saponins from Dioscorea zingiberensis C. H. Wright."Trop J Pharm Res. 2014 Sep;13(8):1339-1345

• 19. [IF=2.998] Lei Lei et al."Preparation of diosgenin from Dioscorea zingiberensis C. H. Wright by stepwise biocatalysis-foam separation-preparative high-performance liquid chromatography (P-HPLC)."Eur Food Res Technol. 2018 Aug;244(8):1447-1452

• 18. [IF=4.759] Mengshun Liu et al."Folding fan mode counter-current chromatography offers fast blind screening for drug discovery. Case study: Finding anti-enterovirus 71 agents from Anemarrhena asphodeloides."J Chromatogr A. 2014 Nov;1368:116

• 17. [IF=5.64] Wu Dousheng et al."Oleanolic Acid Induces the Type III Secretion System of Ralstonia solanacearum."Front Microbiol. 2015 Dec;0:1466

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• 15. Wang, Peng, et al. "Conversion of steroid saponins into diosgenin by catalytic hydrolysis using acid-functionalized ionic liquid under microwave irradiation." Journal of cleaner production 79 (2014): 265-270.https://doi.org/10.1016/j.jclepro.2014.05.041

• 14. 李慧敏,鄭淘,曾藝瓊,范郁冰,李衛(wèi)真,嚴建業(yè),趙利平,鄭慧,楊勇.AHP-CRITIC權重分析法綜合優(yōu)選玉竹全粉改性工藝[J].食品與發(fā)酵工業(yè),2021,47(05):138-146.

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• 12. 周曉,李婧琳,鄒俊波,張小飛,郭東艷,程江雪,史亞軍,石心紅,賈曉斌.粒子設計對參苓白術散在大鼠體內藥動學過程的影響[J].中草藥,2020,51(19):4925-4933.

• 11. 石鴻輝 苑廣偉 廖正睿 等. 不同菌種發(fā)酵對辣木莖葉粉的營養(yǎng)價值及其抗氧化活性的影響[J]. 食品工業(yè)科技 2019 040(009):91-97 104.

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• 1. 趙麗蓉 羅漢 相英龍 等. Box-Benhken響應面法優(yōu)化微波提取黃精總皂苷的條件[J]. 中國現(xiàn)代中藥 2018 20(008):1010-1015.

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本計算器可幫助您計算出特定溶液中溶質的質量、溶液濃度和體積之間的關系，公式為：

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *