• 介紹：

  藥理藥效：有抗癌、神經(jīng)保護(hù)、抗炎、利尿、降血糖及抗肝炎病毒等作用。

• 熔點(diǎn)： 203-205°C

• 沸點(diǎn)： 675.6 °C at 760 mmHg

• 比旋光度： -122 (EtOH aq.)

• 外觀： 白色粉末

• 溶解性： 水：5mg/ml

• 儲存條件： -20℃

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

• 44. [5.3] Jingjing Yang et al."Exploration on the mechanism of “black as lacquer and sweetness as candy” based on the reactions of “crosslinking coloring and Maillard” and “oligosaccharide hydrolysis” during the processing of Radix Rehmanniae."Arabian Journal of Ch

• 43. [6.7] Xin Ye Ji et al."Catalpol alleviates heat stroke-induced liver injury in mice by downregulating the JAK/STAT signaling pathway."PHYTOMEDICINE.2024 Sep;132:155853

• 42. [5.3] Yuyi Wu et al."A gel plaster in the form of nipple cover: A comfortable and safe transdermal delivery method for mammary hyperplasia."INTERNATIONAL JOURNAL OF PHARMACEUTICS.2024 Sep;662:124500

• 41. [IF=4.6] Jingjing Yang et al."Exploration of the Dynamic Variations of the Characteristic Constituents and the Degradation Products of Catalpol during the Process of Radix Rehmanniae."MOLECULES".2024 Jan;29(3):705

• 40. [IF=3.5] Yuanjun Li et al."Transcriptome Analysis Provides Insights into Catalpol Biosynthesis in the Medicinal Plant Rehmannia glutinosa and the Functional Characterization of RgGES Genes."Genes.2024 Feb;15(2):155

• 39. [IF=7.9] Shuai Chen et al."Catalpol attenuates osteoporosis in ovariectomized rats through promoting osteoclast apoptosis via the Sirt6-ERα-FasL axis."PHYTOMEDICINE.2024 Jan;123:155262

• 38. [IF=3.9] Ying Zhang et al."Potential benefits of Rehmanniae Radix after ancient rice-steaming process in promotion of antioxidant activity in rats' health."Food Science & Nutrition.2023 Jun;:

• 37. [IF=7.5] Si Li et al."Catalpol rescues cognitive deficits by attenuating amyloid β plaques and neuroinflammation."BIOMEDICINE & PHARMACOTHERAPY.2023 Sep;165:115026

• 36. [2.65] Minghui Wu et al."Catalpol Regulates Oligodendrocyte Regeneration and Remyelination by Activating the GEF-Cdc42/Rac1 Signaling Pathway in EAE Mice."Evidence-based Complementary and Alternative Medicine.2022 Nov 25;2022:7074157

• 35. [IF=3.978] Du Jikun et al."Catalpol Ameliorates Neurotoxicity in N2a/APP695swe Cells and APP/PS1 Transgenic Mice."NEUROTOXICITY RESEARCH.2022 Jun;:1-12

• 34. [IF=2.759] Yuxi Di et al."Catalpol Inhibits Tregs-to-Th17 Cell Transdifferentiation by Up-Regulating Let-7g-5p to Reduce STAT3 Protein Levels."Yonsei Med J. 2022 Jan; 63(1): 56–65

• 33. [IF=1.982] Lili Song et al."Metabolism of Du Zhong Formula in rats using UPLC-Q-TOF/MS."J Mass Spectrom. 2022 Jan;57(1):e4795

• 32. [IF=2.984] Linluo Zhang et al."Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway."Peerj. 2022 Jan;10:e12759

• 31. [IF=3.935] Yong-Sheng Wu et al."Chemical profiling of Callicarpa nudiflora and its effective compounds identification by compound-target network analysis."J Pharmaceut Biomed. 2020 Apr;182:113110

• 30. [IF=4.162] Weixin Hou et al."The Jieduan-Niwan (JDNW) Formula Ameliorates Hepatocyte Apoptosis: A Study of the Inhibition of E2F1-Mediated Apoptosis Signaling Pathways in Acute-on-Chronic Liver Failure (ACLF) Using Rats."Drug Des Dev Ther. 2021; 15: 3845–3862

• 29. [IF=4.183] Wan Gong et al."Rehmannia glutinosa Libosch Extracts Prevent Bone Loss and Architectural Deterioration and Enhance Osteoblastic Bone Formation by Regulating the IGF-1/PI3K/mTOR Pathway in Streptozotocin-Induced Diabetic Rats."Int J Mol Sci. 2019 Jan;20(16

• 28. [IF=4.225] Yang Fan et al."Catalpol Protects Against Pulmonary Fibrosis Through Inhibiting TGF-β1/Smad3 and Wnt/β-Catenin Signaling Pathways."Front Pharmacol. 2021 Jan;11:2472

• 27. [IF=4.225] Yang Chunjing et al."Neuroprotective Effect of Catalpol via Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Mechanisms."Front Pharmacol. 2020 May;11:690

• 26. [IF=4.36] Chenglin Song et al."Deciphering the mechanism of Fang-Ji-Di-Huang-Decoction in ameliorating psoriasis-like skin inflammation via the inhibition of IL-23/Th17?cell axis."J Ethnopharmacol. 2021 Dec;281:114571

• 25. [IF=6.6] Longtai You et al."Catalpol Protects ARPE-19 Cells against Oxidative Stress via Activation of the Keap1/Nrf2/ARE Pathway."Cells-Basel. 2021 Oct;10(10):2635

• 24. [IF=2.1] Yun Han et al."Antiangiogenic effects of catalpol on rat corneal?neovascularization."Mol Med Rep. 2018 Feb;17(2):2187-2194

• 23. [IF=2.479] Yang Tao et al."Effect of catalpol on remyelination through experimental autoimmune encephalomyelitis acting to promote Olig1 and Olig2 expressions in mice."Bmc Complem Altern M. 2017 Dec;17(1):1-15

• 22. [IF=4.411] Dan-Dan Tian et al."Pharmacokinetic Evaluation of Clozapine in Concomitant Use of Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, or Fructus Gardeniae in Rats."Molecules. 2016 Jun;21(6):696

• 21. [IF=4.411] Wei Wang et al."In Vitro Effects of Concomitant Use of Herbal Preparations on Cytochrome P450s Involved in Clozapine Metabolism."Molecules. 2016 May;21(5):597

• 20. [IF=4.545] Chao Lin et al."Catalpol protects glucose-deprived rat embryonic cardiac cells by inducing mitophagy and modulating estrogen receptor."Biomed Pharmacother. 2017 May;89:973

• 19. [IF=4.759] Mingzhen He et al."Application of characteristic ion filtering with ultra-high performance liquid chromatography quadrupole time of flight tandem mass spectrometry for rapid detection and identification of chemical profiling in Eucommia ulmoides Oliv."J C

• 18. [IF=6.799] Yun Tang et al."Quantifying orientational regeneration of injured neurons by natural product concentration gradients in a 3D microfluidic device."Lab Chip. 2018 Mar;18(6):971-978

• 17. Wang, Wei, Dan-Dan Tian, and Zhang-Jin Zhang. "In Vitro Effects of Concomitant Use of Herbal Preparations on Cytochrome P450s Involved in Clozapine Metabolism."?Molecules?21.5 (2016): 597.https://doi.org/10.3390/molecules21050597

• 16. He, Mingzhen, et al. "Application of characteristic ion filtering with ultra-high performance liquid chromatography quadrupole time of flight tandem mass spectrometry for rapid detection and identification of chemical profiling in Eucommia ulmoides Oliv."

• 15. Lin, Chao, et al. "Catalpol protects glucose-deprived rat embryonic cardiac cells by inducing mitophagy and modulating estrogen receptor." Biomedicine & Pharmacotherapy 89 (2017): 973-982.https://doi.org/10.1016/j.biopha.2017.02.069

• 14. Yang, Tao, et al. "Effect of catalpol on remyelination through experimental autoimmune encephalomyelitis acting to promote Olig1 and Olig2 expressions in mice." BMC complementary and alternative medicine 17.1 (2017): 1-15.https://doi.org/10.1186/s12906-017

• 13. Yang, Chunjing, et al. "Neuroprotective effect of catalpol via anti-oxidative, anti-inflammatory, and anti-apoptotic mechanisms." Frontiers in Pharmacology 11 (2020): 690.https://doi.org/10.3389/fphar.2020.00690

• 12. 化寶軍,趙世莉,蘇妍妍,楊椹.梓醇對急性腎損傷大鼠TLR4/NF-κB通路及腎小球內(nèi)皮損傷的影響[J].中國中西醫(yī)結(jié)合腎病雜志,2020,21(12):1042-1046+1137.

• 11. 李盡文,宋代博,李苑華,麥鍵城,劉詠倩,李莉.梓醇對宮頸癌HeLa細(xì)胞增殖及凋亡作用的研究[J].山東化工,2020,49(17):43-45.

• 10. 陶玉菡,許惠琴,李莉,農(nóng)偉虎,李偉.生地、山茱萸抑制和清除糖基化產(chǎn)物的效應(yīng)成分研究[J].中藥藥理與臨床,2013,29(04):30-33.

• 9. 周炳文, 鐘曉明, 黃真. 玄參環(huán)烯醚萜苷熱回流提取工藝的優(yōu)化[J]. 中成藥, 2018, 040(006):1292-1297.

• 8. 蒙雄裕, 徐良, 李華強(qiáng),等. 用RP-HPLC法測定天目地黃中梓醇和毛蕊花糖苷的含量[J]. 藥學(xué)服務(wù)與研究, 2015, 15(004):273-276.

• 7. 陸春紅, 許惠琴, 劉凱,等. 生地環(huán)烯醚萜苷類成分對AGEs損傷HUVEC的保護(hù)作用[J]. 南京中醫(yī)藥大學(xué)學(xué)報(bào), 2015, 31(001):55-59.

• 6. 李強(qiáng), 胡晶紅, 張永清,等. 曬干與烘干生地黃產(chǎn)量和質(zhì)量比較[J]. 山東中醫(yī)雜志, 2013(09):58-59+77.

• 5. 王素云, 盧穎, 蔡丹鳳,等. 基于雌激素受體探討梓醇對抗糖剝奪心肌細(xì)胞損傷的作用[J]. 中國藥理學(xué)通報(bào), 2019.

• 4. 和大奎, 朱文學(xué), 于斌,等. 地黃浸膏超聲真空干燥特性和動(dòng)力學(xué)研究[J]. 江蘇農(nóng)業(yè)科學(xué), 2017, 45(013):157-164.

• 3. 李民,辛杰,王春艷,李民,張淹.地黃中梓醇含量與產(chǎn)區(qū)相關(guān)性研究[J].中國藥物評價(jià),2014,31(04):212-214.

• 2. 張路 王春艷 李士棟 等. 響應(yīng)面設(shè)計(jì)優(yōu)化地黃中梓醇的提取工藝研究[J]. 中國藥物評價(jià) 2015 000(001):12-16.

• 1. 周霞 張文倩 劉炬 李麗 劉付紅 劉炳男.從血管內(nèi)皮生長因子及其受體調(diào)控角度探討地黃梓醇促血管新生作用及分子機(jī)制研究[J].實(shí)用心腦肺血管病雜志 2020 28(02):64-68.

輸入產(chǎn)品批號：

本計(jì)算器可幫助您計(jì)算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *