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• 產(chǎn)品描述： CX546 is a first-generation and selective benzamide-type positive AMPAR modulator. CX546 is a prototypical ampakine agent and has antipsychotic effects

• 靶點(diǎn)： AMPA Receptor;Autophagy;?iGluR

• 體內(nèi)研究：
  Treatment with the ampakine CX614 (intraperitoneal injection) markedly and reversibly increase brain-derived neurotrophic factor (BDNF) mRNA and protein levels in cultured rat entorhinal/hippocampal slices

• 參考文獻(xiàn)：
  1. Lauterborn JC, et al. Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons. J Neurosci. 2000 Jan 1;20(1):8-21. 2. Lipina T, et al. The ampakine CX546 restores the prepulse inhibition and latent inhibition deficits in mGluR5-deficient mice. Neuropsychopharmacology. 2007 Apr;32(4):745-56.

• 溶解性： DMSO  :  100  mg/mL  (404.38  mM;  Need  ultrasonic)    Ethanol  :  100  mg/mL  (404.38  mM;  Need  ultrasonic)    H2O  :  2  mg/mL  (8.09  mM;  Need  ultrasonic)

• 保存條件： 2-8℃

• 配置溶液濃度參考：
  

  	1mg	5mg	10mg
  1 mM	4.044 ml	20.219 ml	40.438 ml
  5 mM	0.809 ml	4.044 ml	8.088 ml
  10 mM	0.404 ml	2.022 ml	4.044 ml
  50 mM	0.081 ml	0.404 ml	0.809 ml

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

輸入產(chǎn)品批號(hào)：

本計(jì)算器可幫助您計(jì)算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *