黃連堿

    
分析標(biāo)準(zhǔn)品,HPLC≥98%

Coptisine

源葉
B20560 一鍵復(fù)制產(chǎn)品信息
3486-66-6
C19H14NO4+
320.32
MFCD03792689
貨號(hào) 規(guī)格 價(jià)格 上海 北京 武漢 南京 購(gòu)買數(shù)量
B20560-10mg 分析標(biāo)準(zhǔn)品,HPLC≥98% ¥350.00 >10 - - -
B20560-20mg 分析標(biāo)準(zhǔn)品,HPLC≥98% ¥550.00 >10 3 2 1
產(chǎn)品介紹 參考文獻(xiàn)(60篇) 質(zhì)檢證書(shū)(COA) 摩爾濃度計(jì)算器 相關(guān)產(chǎn)品

產(chǎn)品介紹

熔點(diǎn): 212-217 °C
外觀: 淺黃色針狀結(jié)晶 (乙醇)
溶解性: 極略微溶于水,  微溶于乙醇,  溶于堿
儲(chǔ)存條件: 2-8℃
注意: 部分產(chǎn)品我司僅能提供部分信息,我司不保證所提供信息的權(quán)威性,僅供客戶參考交流研究之用。

參考文獻(xiàn)(60篇)

55. [IF=4.9] Xueyu Pu et al."Lipids Extracted from Mycobacterial Membrane and Enveloped PLGA Nanoparticles for Encapsulating Antibacterial Drugs Elicit Synergistic Antimicrobial Response against Mycobacteria."MOLECULAR PHARMACEUTICS".2024;21(5):2238–2249 54. [IF=5.4] Sihao Zhang et al."Chang-Kang-Fang alleviates diarrhea predominant irritable bowel syndrome (IBS-D) through inhibiting TLR4/NF-κB/NLRP3 pathway."JOURNAL OF ETHNOPHARMACOLOGY".2024 Apr;:118236 53. [IF=5.4] Wenjuan Ma et al."Uncovering the key pharmacodynamic material basis and possible molecular mechanism of Xiaoke formulation improve insulin resistant through a comprehensive investigation."JOURNAL OF ETHNOPHARMACOLOGY.2024 Apr;323:117752 52. [IF=7.9] Shan Zhang et al."Enhancing β-Cell Function and Identity in type 2 diabetes: The Protective Role of Coptis deltoidea C. Y. Cheng et Hsiao via Glucose Metabolism Modulation and AMPK Signaling Activation."PHYTOMEDICINE.2024 Jan;:155396 51. [IF=2.9] Qi Ying et al."Sanhuang Xiexin Decoction Ameliorates TNBC By Modulating JAK2-STAT3 and Lipid Metabolism."Chinese Journal of Integrative Medicine.2023 Nov;:1-10 50. [IF=7.9] Min Zhao et al."N6-methyladenosine modification of TSC1 mRNA contributes to macrophage polarization regulated by Coptisine in DSS-induced ulcerative colitis."PHYTOMEDICINE.2023 Oct;:155153 49. [IF=4.6] Fengge YANG et al."Deciphering chemical and metabolite profiling of Chang-Kang-Fang by UPLC-Q-TOF-MS/MS and its potential active components identification."Chinese Journal of Natural Medicines.2023 Jun;21:459 48. [IF=7.9] Jiangna Yan et al."Blocking LTB4 Signaling-mediated TAMs Recruitment by Rhizoma Coptidis Sensitizes Lung Cancer to Immunotherapy."PHYTOMEDICINE.2023 Jul;:154968 47. [IF=6.5] Wei Liu et al."Genome-wide analysis of bHLH gene family in Coptis chinensis provides insights into the regulatory role in benzylisoquinoline alkaloid biosynthesis."PLANT PHYSIOLOGY AND BIOCHEMISTRY.2023 Aug;201:107846 46. [IF=3.571] Ning Zhou et al."Exploring the efficacy mechanism and material basis of three processed Coptidis Rhizoma via metabolomics strategy."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2023 Aug;232:115450 45. [IF=6.656] Ning Zhou et al."Characterizing the specific mechanism of series processed Coptidis Rhizoma by multi-organ metabolomics combined with network pharmacology and molecular docking."PHYTOMEDICINE.2023 Jun;114:154804 44. [IF=3.614] Vinay Naithani et al."Preparation of open tubular capillary column covalently coated with polystyrene sulfonate with 4,4′-Azobis(4-cyanopentanoyl chloride) as polymerization initiator for electrochromatographic separation of alkaloids, sulfonamides, and p 43. [IF=0] Xiaoming Yin et al."Assessment of alkaloids from the stems of 14 Berberis species in China."Separation Science Plus.2022 Dec;:202200114 42. [IF=7.419] Yanlu Liu et al."Coptisine protects against hyperuricemic nephropathy through alleviating inflammation, oxidative stress and mitochondrial apoptosis via PI3K/Akt signaling pathway."BIOMEDICINE & PHARMACOTHERAPY.2022 Dec;156:113941 41. [IF=3.024] Xuan Yu et al."An innovative extraction strategy for herbal medicine by adopting p-sulphonatocalix[6]/[8]arenes."PHYTOCHEMICAL ANALYSIS 40. [IF=6.656] Ye Yang et al."Coptis chinensis polysaccharides dynamically influence the paracellular absorption pathway in the small intestine by modulating the intestinal mucosal immunity microenvironment."PHYTOMEDICINE.2022 Sep;104:154322 39. [IF=1.345] Ya-Li Zhang et al."Coptisine suppresses proliferation and inhibits metastasis in human pancreatic cancer PANC-1 cells."J Asian Nat Prod Res. 2020;22(5):452-463 38. [IF=3.004] Kai Zhang et al."Untargeted metabolomics reveals the synergistic mechanisms of Yuanhu Zhitong oral liquid in the treatment of primary dysmenorrhea."J Chromatogr B. 2021 Feb;1165:122523 37. [IF=3.463] Xiao-Meng Liu et al."Comparative transcriptome analysis provides novel insights into the molecular mechanism of berberine biosynthesis in Coptis chinensis."Sci Hortic-Amsterdam. 2022 Jan;291:110585 36. [IF=3.935] Meng Chen et al."Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate."J Pharmaceut Biomed. 2021 Feb;195:113820 35. [IF=3.935] Yang Song et al."Pharmacokinetics, tissue distribution and plasma protein binding rate of palmatine following intragastric and intravenous administration in rats using liquid chromatography tandem mass spectrometry."J Pharmaceut Biomed. 2021 Sep;203:11422 34. [IF=3.963] Zhong-min Zhao et al."Anti-phytopathogenic activity and the possible mechanisms of action of isoquinoline alkaloid sanguinarine."Pestic Biochem Phys. 2019 Sep;159:51 33. [IF=4.845] Xiaohong Zhang et al."Laboratory bioassay, greenhouse experiment and 3D-QSAR studies on berberine analogues: a search for new herbicides based on natural products."Pest Manag Sci. 2021 Apr;77(4):2054-2067 32. [IF=5.81] Zhao Jing et al."Intra-Herb Interactions: Primary Metabolites in Coptidis Rhizoma Extract Improved the Pharmacokinetics of Oral Berberine Hydrochloride in Mice."Front Pharmacol. 2021 Jun;0:1426 31. [IF=6.023] Maiquan Li et al."Discovery of Keap1?Nrf2 small?molecule inhibitors from phytochemicals based on molecular docking."Food Chem Toxicol. 2019 Nov;133:110758 30. [IF=6.4] Jing Zhao et al."Natural Nano-Drug Delivery System in Coptidis Rhizoma Extract with Modified Berberine Hydrochloride Pharmacokinetics."Int J Nanomed. 2021; 16: 6297–6311 29. [IF=1.618] Yang Yanfang et al."Determination of Alkaloid Contents in Various Tissues of Coptis Chinensis Franch. by Reversed Phase-High Performance Liquid Chromatography and Ultraviolet Spectrophotometry."J Chromatogr Sci. 2017 May;55(5):556-563 28. [IF=1.618] Li Jiang-Yan et al."Seasonal Variation of Alkaloid Contents and Anti-Inflammatory Activity of Rhizoma coptidis Based on Fingerprints Combined with Chemometrics Methods."J Chromatogr Sci. 2015 Aug;53(7):1131-1139 27. [IF=2.795] Yue Xiao et al."Berberine activates bitter taste responses of enteroendocrine STC-1 cells."Mol Cell Biochem. 2018 Oct;447(1):21-32 26. [IF=3.197] Bingxin Ma et al."Coptis chinensis inflorescence ameliorates hyperglycaemia in 3T3-L1 preadipocyte and streptozotocin-induced diabetic mice."J Funct Foods. 2016 Mar;21:455 25. [IF=3.396] Liang Jie et al."Expression and functional activity of bitter taste receptors in primary renal tubular epithelial cells and M-1 cells."Mol Cell Biochem. 2017 Apr;428(1):193-202 24. [IF=3.935] Ka-Yan Kwok et al."Quality evaluation of commercial Huang-Lian-Jie-Du-Tang based on simultaneous determination of fourteen major chemical constituents using high performance liquid chromatography."J Pharmaceut Biomed. 2013 Nov;85:239 23. [IF=4.759] Lvhuan Wang et al."Online screening of acetylcholinesterase inhibitors in natural products using monolith-based immobilized capillary enzyme reactors combined with liquid chromatography-mass spectrometry."J Chromatogr A. 2018 Aug;1563:135 22. [IF=6.023] Ling Zhu et al."Coptis chinensis inflorescence extract protection against ultraviolet-B-induced phototoxicity, and HPLC–MS analysis of its chemical composition."Food Chem Toxicol. 2012 Jul;50:2584 21. Chen, Meng, et al. "Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate." Journal of Pharmaceutical and Biomedical Analysis 195 (2021): 113820.https:// 20. Yue, Xiao, et al. "Berberine activates bitter taste responses of enteroendocrine STC-1 cells." Molecular and cellular biochemistry 447.1 (2018): 21-32.https://doi.org/10.1007/s11010-018-3290-3 19. Ma, Bingxin, et al. "Coptis chinensis inflorescence ameliorates hyperglycaemia in 3T3-L1 preadipocyte and streptozotocin-induced diabetic mice." Journal of Functional Foods 21 (2016): 455-462.https://doi.org/10.1016/j.jff.2015.12.021 18. Liang, Jie, et al. "Expression and functional activity of bitter taste receptors in primary renal tubular epithelial cells and M-1 cells." Molecular and cellular biochemistry 428.1-2 (2017): 193-202.https://doi.org/10.1007/s11010-016-2929-1 17. Yang, Yanfang, et al. "Determination of alkaloid contents in various tissues of Coptis chinensis Franch. by reversed phase-high performance liquid chromatography and ultraviolet spectrophotometry." Journal of chromatographic science 55.5 (2017): 556-563. h 16. Zhu, Ling, et al. "Coptis chinensis inflorescence extract protection against ultraviolet-B-induced phototoxicity, and HPLC–MS analysis of its chemical composition." Food and chemical toxicology 50.7 (2012): 2584-2588.https://doi.org/10.1016/j.fct.2012.04.0 15. 康念欣,袁炎炎,張瀟,路穎慧,李晴霞,李飛,譚鵬.酒黃連HPLC特征圖譜的建立及聚類分析和主成分分析[J].世界科學(xué)技術(shù)-中醫(yī)藥現(xiàn)代化,2020,22(08):2790-2798. 14. 紀(jì)萬(wàn)里,周澤華,王婷婷,安叡,梁琨,王新宏.基于UPLC-LTQ-Orbitrap-MS方法分析半夏瀉心湯化學(xué)成分[J].藥物分析雜志,2020,40(10):1736-1750. 13. 王盼,儲(chǔ)全根,軒云,蔡正銀.抵當(dāng)陷胸湯HPLC-MS指紋圖譜研究[J].時(shí)珍國(guó)醫(yī)國(guó)藥,2020,31(12):2937-2940. 12. 李聽(tīng)弦 李蒙 張志 等. 一測(cè)多評(píng)法測(cè)定不同味連飲片中6個(gè)生物堿類成分的含量[J]. 藥物分析雜志 2018 038(007):1132-1138. 11. 張瀟, 張亞麗, 苗祥貞,等. 黃連不同炮制品及組分的抗腫瘤活性與6種生物堿含量相關(guān)性研究[J]. 中華中醫(yī)藥雜志, 2019, v.34(06):350-353. 10. 趙露, 江健梅, 孟琦,等. 白屈菜生育期內(nèi)生物堿含量的變化規(guī)律[J]. 吉林農(nóng)業(yè)大學(xué)學(xué)報(bào), 2017(5):590-595. 9. 米佳, 賀文達(dá), 梁心怡,等. 黃連肉桂藥對(duì)指紋圖譜的聚類分析及多指標(biāo)的定量分析[J]. 時(shí)珍國(guó)醫(yī)國(guó)藥, 2019, 30(01):83-86. 8. 皮文霞 朱鑫仙 方婷 等. HPLC同時(shí)測(cè)定"三熱論"方各純化部位中藥根堿、表小檗堿、黃連堿、巴馬汀和小檗堿的含量[J]. 中國(guó)實(shí)驗(yàn)方劑學(xué)雜志 2012 18(14):110-113. 7. 李聽(tīng)弦, 李蒙, 張志,等. 基于高效液相色譜指紋圖譜及紅外光譜評(píng)價(jià)黃連及其炮制品質(zhì)量差異[J]. 中南藥學(xué), 2019, 017(004):556-560. 6. 曹一佳 曲玉霞 孫雨 等. UPLC-MS/MS法同時(shí)測(cè)定砂連和胃膠囊中10種化合物含量[J]. 國(guó)際藥學(xué)研究雜志 2020 v.47(01):76-81. 5. 房康, 吳高榮, 王輝,等. 黃連解毒湯自沉淀化學(xué)成分及其抗PC12細(xì)胞損傷研究[J]. 中草藥, 2017(18). 4. 柳鑫,楊艷芳,宋紅萍,張小波,黃璐琦,吳和珍.基于MaxEnt和ArcGIS的黃連生長(zhǎng)適宜性區(qū)劃研究[J].中國(guó)中藥雜志,2016,41(17):3186-3193. 3. 李文芳 王曉明 潘桂湘 等. LC-MS/MS測(cè)定養(yǎng)血清腦顆粒中15個(gè)生物堿成分的含量[J]. 遼寧中醫(yī)雜志 2017(10):134-136+229. 2. 尚嬋 李孟璇 李海波 何亮偉 孟兆青 黃文哲 王振中 丁崗 楊中林 蕭偉.LC-MS/MS同時(shí)測(cè)定痛安注射液中13個(gè)成分的含量[J].中國(guó)中藥雜志 2017 42(10):1901-1907. 1. 王永占 沈勇 史曉倩 韓玙 楊生超 梁艷麗 謝世清.HPLC法同時(shí)測(cè)定云黃連中四種生物堿的含量[J].中國(guó)藥師 2013 16(07):947-949.

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