| 產(chǎn)品描述： | Ceftibuten (Sch-39720) dihydrate, an antibiotic, is an orally active cephalosporin, possesses potent activity in vitro against a wide range of gram-negative and certain gram-positive pathogens |
| 靶點： |
β-lactam;Antibacterial;Antibiotic |
| 體內(nèi)研究： |
Ceftibuten, a biologically stableβ-lactam antibiotic, has been shown to be transported by the small peptide transport system, to have relatively high affinity for the carrier and to show clear stereoselective and proton-gradient dependent transport characteristics in rat intestinal brush-border membrane vesicles |
| 參考文獻(xiàn)： |
1. Kearns GL, et al. Single-dose pharmacokinetics of ceftibuten (SCH 39720) in infants and children. Antimicrob Agents Chemother. 1991;35(10):2078-2084. 2. Shawar R, et al. Comparative in vitro activity of ceftibuten (Sch 39720) against bacterial enteropathogens. Antimicrob Agents Chemother. 1989;33(5):781-784. 3. Tamai I, et al. Functional expression of intestinal dipeptide/beta-lactam antibiotic transporter in Xenopus laevis oocytes. Biochem Pharmacol. 1994;48(5):881-888. |
| 溶解性： |
H2O : 100 mg/mL (223.98 mM; ultrasonic and warming and heat to 80°C) DMSO : 100 mg/mL (223.98 mM; Need ultrasonic) |
| 保存條件： |
2-8℃ |
| 配置溶液濃度參考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.24 ml |
11.199 ml |
22.399 ml |
| 5 mM |
0.448 ml |
2.24 ml |
4.48 ml |
| 10 mM |
0.224 ml |
1.12 ml |
2.24 ml |
| 50 mM |
0.045 ml |
0.224 ml |
0.448 ml |
|
| 注意： |
部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。 |
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危險品化學(xué)品經(jīng)營許可證（不帶存儲）
營業(yè)執(zhí)照(三證合一)
北京