lucanthone

    98%

lucanthone

源葉(MedMol)
S85514
479-50-5
C20H24N2OS
340.48236
硫坎酮;甲硫蒽酮;硫蒽酮;硫坎酮;1-((2-(二乙基氨基)乙基)氨基)-4-甲基硫雜蒽-9-酮;1-(2-diethylaminoethylamino)-4-(methyl)thioxanthen-9-one;lucanthone;1-[[2-(Diethylamino)ethyl]amino]-4-methyl-9H-thioxanthen-9-one;Lycanthone
品牌 貨號 產(chǎn)品規(guī)格 價格(RMB) 庫存(上海) 北京 武漢 南京 購買數(shù)量
源葉(MedMol) S85514-5mg 98% ¥300.00元 6 - - -
源葉(MedMol) S85514-25mg 98% ¥900.00元 6 - - -
源葉(MedMol) S85514-100mg 98% ¥2200.00元 3 - - -
產(chǎn)品介紹 參考文獻(1篇) 質檢證書(COA) 摩爾濃度計算器 相關產(chǎn)品

產(chǎn)品介紹

Lucanthone is an inhibitor of Apurinic endonuclease-1 (APE-1).
產(chǎn)品描述: Lucanthone is an inhibitor of Apurinic endonuclease-1 (APE-1).
靶點: Autophagy;DNA/RNA Synthesis;DNA/RNASynthesis;Autophagy
細胞實驗: Cell viability is assessed by MTT assay. Cells are seeded into 96-well microculture plates at 10,000 cells per well and allowed to attach for 24 h. Cells are then treated with Lucanthone (0, 0.5, 1, 5, 10, 20 and 40 μM), Chloroquine, Vorinostat, or combinations for 72 h. Following drug treatment, MTT is added and cell viability is quantified using a BioTek microplate reader. Effects on cell viability are also determined by measuring ATP levels using the ATPlite assay system and by trypan blue exclusion. Pro-apoptotic effects following in vitro drug exposure are quantified by propidium iodide (PI) staining and fluorescence-activated cell sorting (FACS) analysis of sub-G0/G1 DNA content
參考文獻: 1. Carew JS,etal.Lucanthone is a novel inhibitor of autophagy that induces cathepsin D-mediated apoptosis.J Biol Chem. 2011 Feb 25;286(8):6602-13. 2. Chowdhury SM,etal.Graphene nanoribbons as a drug delivery agent for lucanthone mediated therapy of glioblastoma multiforme.Nanomedicine. 2015 Jan;11(1):109-18.
溶解性: Soluble  in  DMSO
保存條件: 2-8℃
配置溶液濃度參考:
1mg 5mg 10mg
1 mM 2.937 ml 14.685 ml 29.37 ml
5 mM 0.587 ml 2.937 ml 5.874 ml
10 mM 0.294 ml 1.469 ml 2.937 ml
50 mM 0.059 ml 0.294 ml 0.587 ml
注意: 部分產(chǎn)品我司僅能提供部分信息,我司不保證所提供信息的權威性,僅供客戶參考交流研究之用。

質檢證書(COA)

如何獲取質檢證書(COA)?
請輸入貨號和一個與之匹配的批號。
例如:
批號:JS298415 貨號:S20001-25g
在貨品標簽上如何找到貨號和批號?

摩爾濃度計算器

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

=
×
×

相關產(chǎn)品