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ALC-0315

    98%

[(4-Hydroxybutyl)azanediyl]di(hexane-6,1-diyl) bis(2-hexyldecanoate)

源葉(MedMol)
S89624
2036272-55-4
C48H95NO5
766.29
ALC-0315; ALC 0315; ALC0315;
品牌 貨號(hào) 產(chǎn)品規(guī)格 價(jià)格(RMB) 庫(kù)存（上海） 北京 武漢 南京 購(gòu)買(mǎi)數(shù)量
源葉(MedMol) S89624-5mg 98% ￥425.00元 >10 - - -
源葉(MedMol) S89624-10mg 98% ￥540.00元 >10 - - -
源葉(MedMol) S89624-25mg 98% ￥800.00元 >10 - - -
源葉(MedMol) S89624-100mg 98% ￥1630.00元 9 - - -
產(chǎn)品介紹 參考文獻(xiàn)(1篇) 質(zhì)檢證書(shū)(COA) 摩爾濃度計(jì)算器 相關(guān)產(chǎn)品

產(chǎn)品介紹

ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine
產(chǎn)品描述： ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine
靶點(diǎn)： Liposome;SARS-CoV
體外研究： ALC-0315 用于形成疫苗接種研究的脂質(zhì)納米顆粒
參考文獻(xiàn)： 1. Moghimi SM. Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines. Mol Ther. 2021;29(3):898-900. 2. Ferraresso F, Strilchuk AW, Juang LJ, Poole LG, Luyendyk JP, Kastrup CJ. Comparison of DLin-MC3-DMA and ALC-0315 for siRNA Delivery to Hepatocytes and Hepatic Stellate Cells. Mol Pharm. 2022;19(7):2175-2182.
溶解性： Soluble  in  DMSO、Ethanol
保存條件： -20℃
配置溶液濃度參考：
1mg 5mg 10mg
1 mM 1.305 ml 6.525 ml 13.05 ml
5 mM 0.261 ml 1.305 ml 2.61 ml
10 mM 0.13 ml 0.652 ml 1.305 ml
50 mM 0.026 ml 0.13 ml 0.261 ml
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質(zhì)檢證書(shū)(COA)

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批號(hào)：JS298415 貨號(hào)：S20001-25g
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摩爾濃度計(jì)算器

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