YS-49 is a PI3K/Akt (a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells. YS-49 inhibits angiotensin II (Ang II)-stimulated proliferation of VSMCs via induction of heme oxygenase (HO)-1. YS-49 is also an isoquinoline compound alkaloid, has a strong positive inotropic action through activation of cardiac β-adrenoceptors
溶解性:
DMSO : 100 mg/mL (258.88 mM; Need ultrasonic) H2O : 10 mg/mL (25.89 mM; ultrasonic and warming and heat to 60°C)