強大的NO合酶,NADPH氧化酶和NADPH細胞色素P450氧化還原酶抑制劑;Potent NO synthase, NADPH oxidases and NADPH cytochrome P450 oxidoreductase inhibitor;有效并具可逆性的氧化氮合成酶抑制劑,來自于巨噬細胞和內(nèi)皮細胞。該抑制劑也抑制其它的黃素酶(flavoenzymes), 如中性粒細胞NADPH氧化酶。Diphenyleneiodonium chloride (DPI) is an inhibitor of NADPH oxidase and also a potent, irreversible, and time-, temperature-dependent iNOS/eNOS inhibitor. Diphenyleneiodonium chloride (DPI) also functions as a TRPA1 activator and selectively inhibits intracellular reactive oxygen species (ROS).;Diphenyleneiodonium chloride (DPI) is an inhibitor of NADPH oxidase and also a potent, irreversible, and time-, temperature-dependent iNOS/eNOS inhibitor. Diphenyleneiodonium chloride (DPI) also functions as a TRPA1 activator and selectively inhibits intracellular reactive oxygen species (ROS).